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From161US$ /night
Check-in
23Feb2026Select date
Check-out
24Feb2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

220 North Main Street, Greenville, South Carolina, United States, 29601
-
Close to Falls Park on the Reedy River
Great
8.6
8.4
/10
4.1
3.8
/5

Hyatt Regency - Greenville, downtown hotel with fitness center near Greenville Downtown Airport

Hyatt Regency Greenville is located in downtown Greenville on NOMA Square, a short walk from over 60 restaurants and shops. The hotel features a state-of-the-art fitness center with Life Fitness treadmills, ellipticals, cross-trainers, and exercise bikes. Guests have access to an outdoor pool, a 24-hour business center with computer access and printers, and 25,000 square feet of conference space. The onsite restaurant, Roost, serves farm-to-table American cuisine with brunch and happy hour options. The hotel offers an airport transfer service to Greenville Downtown Airport, 2 km away.

Additional perks of the hotel

Free weights, circuit weights, ropes, and mats in the fitness center

Dry cleaning/laundry services and an outdoor entertainment area

Jogging paths onsite

Proximity to Bon Secours Wellness Arena, Greenville County Museum of Art, and The Children's Museum of the Upstate

Rooms

All 327 rooms at Hyatt Regency Greenville include premium bedding, laptop-compatible safes, and air conditioning. Some rooms feature a separate furnished seating area and dining area, as well as views of the Blue Ridge Mountains or the hotel's atrium. Each room has a flat-screen TV with cable channels, a coffee maker, and a private bathroom with free toiletries.

Other conveniences

Ironing facilities and tea/coffee makers

Direct dial telephones and CD players

Wheelchair-accessible rooms with grab rails

Skyline or panoramic mountain views in select rooms

Must-do experiences

  • Stroll through Falls Park on the Reedy for stunning views.
  • Try the famous biscuits at Biscuit Head for breakfast bliss.
  • Visit the Upcountry History Museum for local culture and stories.
  • Explore the Greenville Zoo for a fun family outing.
  • Check out the Saturday Market for local crafts and fresh produce.
View all

Choose Your Room

Our listed hotels offer a variety of room types—double rooms, family suites, or deluxe options—all with features like breakfast, flexible cancellation policies, and exclusive deals.
Deluxe King Room
2 persons
360 sq. feet 
1 King-size bed
Bathtub
Air conditioning
King Room Accessible Shower Disability Access
2 persons
345 sq. feet 
1 King-size bed
Shower
Air conditioning
King Room Accessible Tub Disability Access
2 persons
345 sq. feet 
1 King-size bed
Bathtub
Air conditioning
Queen Room Two Queen Beds
2 persons
345 sq. feet 
2 King Size Beds
Coffee machine
Bathtub
Click button to see more rooms
Show all rooms
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Room Rates & Availability Tracker

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Amenities

Thoughtful hotel amenities for a comfortable stay
Facilities: Great
8.7/10Review score

General

  • No smoking on site
  • Free Wi-Fi
  • On-site car park
  • Handicap parking
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Hiking
  • Cycling
  • Bowling
  • Golf course

Guest Parking

  • Electric kettle

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Shops/Commercial services
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Children's menu

Spa & Leisure

  • Seasonal outdoor pool
  • Beach umbrellas
  • Sun loungers
  • Live entertainment
  • Sun terrace
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries
  • Sink

Self-catering

  • Electric kettle

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
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Dining Onsite

Hyatt Regency - Greenville offers an enticing dining experience with Roost Restaurant, where delightful American cuisine takes center stage. The inviting atmosphere and family-friendly settings make it perfect for leisurely meals whether it's breakfast, lunch, or dinner.
Hyatt Regency - Greenville Restaurant photo
Hyatt Regency - Greenville Restaurant photo
Hyatt Regency - Greenville Restaurant photo

Roost Restaurant

American cuisine
Ambiance
Family-friendly with a mix of traditional and modern decor
Key Offerings
Start the day with hearty breakfast options or enjoy a leisurely lunch and dinner. Don't miss the refreshing happy hour and delightful weekend brunch.
Reservation
Reservations recommended.
Open daily for breakfast from 6:30 AM to 10:00 AM, lunch and dinner from 11:30 AM to 9:00 PM.

Hotel Location

220 North Main Street, Greenville, South Carolina, United States, 29601
Map view
220 North Main Street, Greenville, South Carolina, United States, 29601
Nearby
Museum
The Children's Museum of the Upstate
1700 ft
Event hall
Kilgore Lewis House
1800 ft
Church
Christ Episcopal Church
1900 ft
14 S Main St
Dark Corner Distillery
1100 ft
220 N Main St
Noma Square
200 ft
Gallery
The Art Cellar
200 ft
South Main Street Court Square
Joel Roberts Poinsett
1700 ft
650 N Academy St Bon Secours Wellness Arena
Greenville Swamp Rabbits
1900 ft
Gallery
Artists Guild Gallery Of Greenville
100 ft
S Main St
Downtown Greenville
1800 ft
430 N Main St
American Legion
1600 ft
Restaurants
Antonino Bertolo's Pizza and Wine Bar
100 ft
200 N Main St Ste 103
Subway
600 ft
225 N Main St
Jersey Mike's Subs
500 ft
233 N Main St Suite 10
Menkoi Noodle House
800 ft
241 N Main St
Vic's Pizza
600 ft
12 E Coffee St
Sully's Steamers
700 ft
6 East Washington Street
Groucho's Deli
800 ft
20 E Coffee St # SC
Charleston Sports Pub
600 ft
15 W Washington St
Explore Greenville
Explore Greenville
Top Attractions
Activities
Dining
Entertainment
Falls Park on the Reedy
Falls Park on the Reedy
14-minute walk
Scenic park with stunning waterfalls, walking trails, and beautiful gardens. Ideal for relaxation and family outings.
Greenville Zoo
Greenville Zoo
4-minute drive
Home to 300+ animals, the zoo offers engaging exhibits and educational programs, perfect for families with kids.
Upcountry History Museum
Upcountry History Museum
10-minute walk
Showcases local history and culture through interactive exhibits. Features unique artifacts and rotating displays.
Bon Secours Wellness Arena
Bon Secours Wellness Arena
9-minute walk
Versatile venue hosting concerts, sports events, and family shows. Prominent spot for nightlife and entertainment.
Riding Bikes on the Swamp Rabbit Trail
5-minute walk
Biking along this scenic trail offers beautiful views and outdoor fun. Bike rentals available near the trail access.
Yoga at Noma Square
5-minute walk
Relaxing yoga sessions organized at this vibrant public square. Great for unwinding in a lively atmosphere.
Antonino Bertolo's Pizza and Wine Bar
Antonino Bertolo's Pizza and Wine Bar
1-minute walk
Casual eatery specializing in artisanal pizza and a curated wine list. Known for its warm ambiance and local ingredients.
Menkoi Noodle House
Menkoi Noodle House
3-minute walk
Serves authentic ramen and Japanese dishes in a cozy setting. Vegetarian options available; reservations recommended.
Dark Corner Distillery
Dark Corner Distillery
4-minute walk
Offers tastings and tours of locally crafted spirits in a relaxed setting. Ideal for enthusiasts of craft beverages.
The Peace Center
15-minute walk
A cultural hub featuring theater productions, concerts, and community events. Family-friendly shows and a vibrant atmosphere.
Transportation Tips
City Centre
Greenville5 min  ·  1400 ft
Airports
Greenville-Spartanburg International Airport (GSP)34 min  ·  13.8 mi
Asheville Regional Airport (AVL)118 min  ·  48.5 mi
Train
Greenville County Art Museum5 min  ·  1400 ft
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site at USD 7 per day.
Internet
is available in for free.
Breakfast
The hotel offers a full breakfast at the price of US$21 per person per day. 
Children & extra beds
There are no cots provided in a room.  There are no extra beds provided in a room. 
Pets
Pets are allowed on request.
Languages
Spanish, Turkish
Year renovated:
2009
Number of floors:
8
Number of rooms:
325

Guest Reviews & Ratings

What Guests Are Saying?
Review score
Based on 453 verified reviews
8.1/10
Great
74%
Recommend
Cleanliness
8.9/10
Comfort
8.9/10
Facilities
8.7/10
Free Wi-Fi
8.5/10
Location
9.4/10
Staff
8.9/10
Value for money
8.0/10
Pros
Comfortable bed
Friendly staff
Good location
Hotel bar
Sunday brunch
Cons
Noisy room
Room updates
Guest reviews
based on 475 reviews
8.6/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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