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Check-in
20Nov2025Select date
Check-out
21Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

220 North Main Street, Greenville, South Carolina, United States, 29601

Hyatt Regency - Greenville, downtown hotel with fitness center near Greenville Downtown Airport

Hyatt Regency Greenville is located in downtown Greenville on NOMA Square, a short walk from over 60 restaurants and shops. The hotel features a state-of-the-art fitness center with Life Fitness treadmills, ellipticals, cross-trainers, and exercise bikes. Guests have access to an outdoor pool, a 24-hour business center with computer access and printers, and 25,000 square feet of conference space. The onsite restaurant, Roost, serves farm-to-table American cuisine with brunch and happy hour options. The hotel offers an airport transfer service to Greenville Downtown Airport, 2 km away.

Additional perks of the hotel

Free weights, circuit weights, ropes, and mats in the fitness center

Dry cleaning/laundry services and an outdoor entertainment area

Jogging paths onsite

Proximity to Bon Secours Wellness Arena, Greenville County Museum of Art, and The Children's Museum of the Upstate

Rooms

All 327 rooms at Hyatt Regency Greenville include premium bedding, laptop-compatible safes, and air conditioning. Some rooms feature a separate furnished seating area and dining area, as well as views of the Blue Ridge Mountains or the hotel's atrium. Each room has a flat-screen TV with cable channels, a coffee maker, and a private bathroom with free toiletries.

Other conveniences

Ironing facilities and tea/coffee makers

Direct dial telephones and CD players

Wheelchair-accessible rooms with grab rails

Skyline or panoramic mountain views in select rooms

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Choose Your Room

Our listed hotels offer a variety of room types—double rooms, family suites, or deluxe options—all with features like breakfast, flexible cancellation policies, and exclusive deals.
Deluxe King Room
2 persons
33 m² 
1 King-size bed
Bathtub
Air conditioning
King Room Accessible Shower Disability Access
2 persons
32 m² 
1 King-size bed
Shower
Air conditioning
King Room Accessible Tub Disability Access
2 persons
32 m² 
1 King-size bed
Bathtub
Air conditioning
Queen Room Two Queen Beds
2 persons
32 m² 
2 King Size Beds
Coffee machine
Bathtub
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Transportation Tips

Transportation Options

City Centre
Greenville400 m
Airports
Greenville-Spartanburg International (GSP) 22.2 km
Asheville Regional (AVL) 78.1 km
Train
Greenville County Art Museum400 m

Amenities

Thoughtful hotel amenities for a comfortable stay

General

  • No smoking on site
  • Free Wi-Fi
  • On-site car park
  • Handicap parking
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Hiking
  • Cycling
  • Bowling
  • Golf course

Guest Parking

  • Electric kettle

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Shops/Commercial services
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots
  • Children's menu

Spa & Leisure

  • Seasonal outdoor pool
  • Beach umbrellas
  • Sun loungers
  • Live entertainment
  • Sun terrace
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries
  • Sink

Self-catering

  • Electric kettle

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
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Hotel Location

220 North Main Street, Greenville, South Carolina, United States, 29601
Map view
220 North Main Street, Greenville, South Carolina, United States, 29601
Nearby
Museum
The Children's Museum of the Upstate
500 m
Event hall
Kilgore Lewis House
520 m
Church
Christ Episcopal Church
560 m
14 S Main St
Dark Corner Distillery
310 m
220 N Main St
Noma Square
60 m
Gallery
The Art Cellar
60 m
South Main Street Court Square
Joel Roberts Poinsett
510 m
650 N Academy St Bon Secours Wellness Arena
Greenville Swamp Rabbits
560 m
Gallery
Artists Guild Gallery Of Greenville
20 m
S Main St
Downtown Greenville
520 m
430 N Main St
American Legion
470 m
Restaurants
Antonino Bertolo's Pizza and Wine Bar
30 m
200 N Main St Ste 103
Subway
180 m
225 N Main St
Jersey Mike's Subs
150 m
233 N Main St Suite 10
Menkoi Noodle House
230 m
241 N Main St
Vic's Pizza
180 m
12 E Coffee St
Sully's Steamers
190 m
6 East Washington Street
Groucho's Deli
230 m
20 E Coffee St # SC
Charleston Sports Pub
180 m
15 W Washington St
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Check-in
20Nov2025Select date
Check-out
21Nov2025Select date
Rooms and Guests2 Guests, 1 Room